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Vanessa Gambus

Vanessa Gambus
Vanessa Gambus
Master student
M1125 +49-7531-88-xxxx

Bio
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I am a Master’s student in neuroscience, studying how sensory inputs are transformed into neural activity and ultimately behavior in larval zebrafish. I am particularly interested in how past sensory experiences shape ongoing processing and enable flexible, adaptive behavior.

My current work focuses on how stimulus history influences sensorimotor transformations under controlled conditions. Using head-fixed larval zebrafish, I combine quantitative behavioral tracking with precisely controlled visual stimulation to probe how prior inputs bias future responses. A central goal of my project is to link these behavioral effects to their underlying neural dynamics by integrating two-photon microscopy.

embedded larval zebrafish
Image 1: Wildtype larval zebrafish embedded in agarose with tail cut free

I previously worked in the same lab during my Bachelor’s thesis, where I focused on multicolor fluorescent labeling of the nervous system in larval zebrafish using electroporation. I continued this work during a six-month research assistant position, further deepening my interest in experimental neuroscience. Early observations from a recent Master-level course (VTK) suggest that larval zebrafish retain information about previous stimuli and adjust their responses accordingly, providing a strong motivation for my current research.

electroporation of larval zebrafish
Image 2: 4dpf zebrafish larva where electroporation was done with the plasmid gap43EGFP using a 0,1μm tip borosilicate glass pipette; a, b, c: the three positions were the electroporation needle was placed
two-photon scan of electroporated larval zebrafish
Image 3: Electroporated zebrafish larva at 4dpf with gap43-EGFP. a: Maximum z-stack projection of successfully electroporated larval zebrafish (5dpf) b: single stack chosen from two-photon image

Outside the lab, I am involved in university and HTWG theater, mainly working in make-up but occasionally also performing on stage. In my free time, I enjoy trying out new sports, solving escape rooms, and I am currently working towards my scuba diving certification.

Projects
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Methods
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Thesis
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Title Neural correlates of history-dependent sensorimotor processing in larval zebrafish
Type Master thesis
Period 2026/03–present
Summary My Master’s thesis will investigate the behavior of larval zebrafish in response to visual stimuli with varying coherence levels in a head-fixed preparation. The project combines behavioral tracking with visual stimulation and is planned to be extended with two-photon imaging to study the underlying neural activity.

CV
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Positions

2023 Assistant researcher, University of Konstanz

Education

Since 2023 Master of Science in Biological Sciences, University of Konstanz
2018–2023 Bachelor of Science in Biological Sciences, University of Konstanz

Publications
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No publications available.